Endocrine Abstracts

Introduction: Patients with large non-functioning pituitary macroadenomas often have symptoms due to varying degree of hypopituitarism and/or mass effect on visual structures, while presentation with hydrocephalus is extremely uncommon.Case report: We describe an 82-year-old man who was referred to the Neurology department of our hospital because of rapidly progressive memory loss. The patient was in good health until ten weeks earlier, when he insidious...

Introduction: Postprandial hypoglucaemia with hyperinsulinism after laparoscopic gastric bypass is an uncommon complication with an estimated prevalence of 0.2%. Its treatment includes acarbose, diazoxide, somatostatin and GLP-1 analogues or calcium channel blockers in case a strict diet does not work.Case report: A 42-year-old woman with history of gastric bypass in 2005 due to severe obesity (preoperative weight 150 kg) attended our clinic 3 years afte...

Objective: To describe the clinical characteristics and post-surgical outcome of our primary hyperparathyroidism case series.Methods: A retrospective cohort study of primary hyperparathyroidism patients who underwent surgery in the last 10 years in our centre. The medical records were reviewed to extract data. A statistical descriptive analysis was performed using mean and S.D. for continuous variables and percentages for qualitative varia...

Introduction: Thyrotoxic periodic paralysis (TPP) is a complication of hyperthyroidism characterized by muscle paralysis and hypokalemia. It mainly affects male patients of Asian descent. Many patients do not have obvious symptoms and signs of hyperthyroidism, which makes its diagnosis difficult.Case report: A 47-year-old Asian man presented with all four limbs rapidly progressive muscular weakness that caused him inability to walk. He referred a previou...

Background: Women with polycystic ovary syndrome (PCOS) frequently suffer from metabolic disturbances, in particular from pre-diabetes and diabetes. Conflicting results currently exists on the relationship between vitamin D and glucose metabolism. Hence, the aim of our study was to investigate the association of 25-hydroxyvitamin D (25(OH)D) levels and glucose tolerance in PCOS women.Methods: Cross-sectional study including 23 PCOS patients (mean age 27 ...

Background and objective: The incidence of differentiated thyroid carcinoma (DTC) is increasing worldwide. Due to a increased use of improved radiological techniques, especially ultrasound. This study aims to analyze histological characteristics of DTC diagnosed in our hospital in the last fifteen years.Patients and methods: It is a restrospective descriptive study. We have included all operated patients in our center between 2001 and 2015 with a final b...

Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder characterized by varied neurological symptoms. There are two leading theories regarding the pathophysiology: hypertension crisis and endothelial dysfunction.Case reportWe report the case of a 42-year-old patient with history of hypertension. She presented to the emergency department with headache and bilateral loss of vision. She described one previous e...

Introduction: A link between Dopamine agonists and development of impulse control disorders is well recognized in the field of neurology. A similar finding in endocrine patients is emerging.Case report: We report the case of a 38-year-old man with pathological addiction to gambling associated with low dose cabergoline treatment for a mixed growth hormone (GH) and prolactin (PRL)-secreting pituitary adenoma. At the age of 29 he ...

Introduction: Ipilimumab is a monoclonal antibody against the inhibitory CTLA-4 receptor expressed on T cells. It provokes an upregulation of the immune system. It is known to cause neuroendocrine disorders, such as hypophysitis, hyppothyroidism/thyroiditis and adrenal insufficiency. Althought it is stipulated that thyroid.stimulating hormone (TSH) levels should be evaluated before administration of each dose of ipilimumab as a screen for thyroid diyfunction, there is no reque...